This study is a collaborative project which would not have been possible without the support of our partners. This work receives funding from the rapid research response funded by UK Research and Innovation (UKRI), and by the Department of Health and Social Care through the National Institute for Health Research (NIHR). The NIHR have also provided funding for the set-up of the project through the Oxford Biomedical Research Centre (BRC). The study has received funding from the Coalition for Epidemic Preparedness Innovations (CEPI) as part of an urgent call to expand the number of COVID-19 vaccine candidates in development. Funding has also been received from the Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Science (CIFMS). The ‘CSIROxbridge Consortium’ (Principal Investigator Prof. S. S. Vasan) is led by Australia’s science agency CSIRO for ‘High Containment Studies to Support Product Development’ for CEPI.
Preclinical testing of the ChAdOx1 nCoV-19 vaccine is being conducted in collaboration with our partners: Rocky Mountain Laboratories (NIH/NIAID); The ‘CSIROxbridge Consortium’; Public Health England; The Pirbright Institute; Prof. Dr. Stephen Becker at the Institut für Virologie, Philipps University, Marburg. Manufacturing for the current and future clinical trials is being conducted in collaboration with the University of Oxford Clinical Biomanufacturing Facility, Advent Srl (Italy) and SGS Vitrology (Glasgow). Development and scale-up of manufacturing to produce millions of doses is being carried out in partnership with the Vaccine Manufacturing and Innovation Centre (Oxford), Pall Biotech (Portsmouth), Cobra Biologics (Staffordshire), Halix BV (Netherlands), and Oxford Biomedica.